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Titlebook: Gene- and Cell-Based Treatment Strategies for the Eye; Elizabeth P. Rakoczy Book 2015 Springer-Verlag Berlin Heidelberg 2015 Complex eye d

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Laura Weiss Roberts MD, MA,Mark Siegler MD scientific discoveries that contributed, we have endeavored to crystallize the steps that were the most important and presented them in the context of scientific history. The birth of genetics led to the discovery of DNA, understanding of inheritance, variations, and mutations. However, not until t
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https://doi.org/10.1007/978-3-030-46324-3’s congenital amaurosis (LCA) due to . mutations. In the past 7 years, eight different clinical trials have been carried out evaluating safety and efficacy of recombinant virus-mediated delivery of the normal copy of .. The studies have differed in a number of variables, including dose and volume of
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Núria Amigó Grau,Pablo Ortiz Betesh century. In sufferers, the appearance of the fundus is of a characteristic pale colour caused by the loss of the outer retina, retinal pigmented epithelium and choroidal vessels, leading to exposure of the underlying sclera. Visual symptoms begin with reduction of night vision and gradually progre
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Monique M. Elseviers,Marc E. De Broertant role in disease burden and progression. Current therapies focus on inhibition of neovascularization through suppression of the extracellular VEGF pathway. However, these strategies have several disadvantages including the need for monthly injections and the need for direct injections of drug t
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