| 书目名称 | Gene Transfer in the Cardiovascular System |
| 副标题 | Experimental Approac |
| 编辑 | Keith L. March |
| 视频video | |
| 丛书名称 | Developments in Cardiovascular Medicine |
| 图书封面 |  |
| 描述 | The goal of gene transfer is protein expression. a process brought about by the insertion of a gene coding for a foreign protein into target cells resulting in the synthesis of the foreign protein For gene therapy, a tmnsferred therapeutic gene must be expressed at a level beneficial for the patient. This chapter provides an introductory overview of the rapidly evolving field of non-viral approaches for gene delivery to rnarnrnalian cells. Although currently there are fewer ongoing clinical trials using non-viral approaches than those using viral based systems, the number of non-viral trials is increasing. The long range goal of some research groups is the development of a genetically engineered artificial virus targeted to specific cells in the human body. An arurual conference, organized by Cambridge Healthtech Institute entitled "Artificial Self-Assembling Systems for Gene Transfer", brings together researchers interested in this field [1]. Assembly of an artificial virus is very complex; other research groups aim to develop simpler delivery systems consisting of a plasmid combined with delivery agents. Viral-based systems are very successful for gene delivery, but despite their |
| 出版日期 | Book 1997 |
| 关键词 | DNA; cardiovascular; gene therapy; gene transfer; genes |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4615-6277-1 |
| isbn_softcover | 978-1-4613-7881-5 |
| isbn_ebook | 978-1-4615-6277-1Series ISSN 0166-9842 |
| issn_series | 0166-9842 |
| copyright | Springer Science+Business Media New York 1997 |
发表于 2025-3-21 16:42:39
