Titlebook: Gene Therapy of Cancer; Methods and Protocol Wolfgang Walther Book 2022Latest edition The Editor(s) (if applicable) and The Author(s), unde

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A qPCR-Based Method for Quantification of Replication Competent Adenovirus (RCA) in Conditionally Reoncerns in clinical usage. Cell-based assays can detect RCA in batches of nonreplicating adenoviral vectors but cannot distinguish RCA from conditionally replicating oncolytic adenoviruses. Considering the great potential in using oncolytic viruses for cancer treatment, there is a need for comprehen

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Visualized Cancer Immunotherapy with Engineered like receptor 5 (TLR5) that can activate robust host immune system, is an excellent adjuvant for cancer immunotherapy with high binding affinity to TLR5. Here, we constructed attenuated . that expresses flagellin B (FlaB) with a controlled expression system to enhance targeted cancer immunotherapy w

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https://doi.org/10.1007/978-1-0716-2441-8CAR-T cells; Suicide gene therapy; Gene replacement; Gene suppression; Oncolytic therapy

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978-1-0716-2443-2The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines

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Sahat M. Pasaribu,Abduh Sudiyantoh the initial intent to repair or replace defective genes. Gene therapy has been adapted for treatment of malignant diseases to improve the outcome of cancer patients. In fact, cancer gene therapy has rapidly gained great interest and evolved into a research field with highest proportion of research