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Titlebook: Gene Therapy for Neurological Disorders and Brain Tumors; E. Antonio Chiocca,Xandra O. Breakefield Book 1998 Springer Science+Business Med

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书目名称Gene Therapy for Neurological Disorders and Brain Tumors
编辑E. Antonio Chiocca,Xandra O. Breakefield
视频video
丛书名称Contemporary Neuroscience
图书封面Titlebook: Gene Therapy for Neurological Disorders and Brain Tumors;  E. Antonio Chiocca,Xandra O. Breakefield Book 1998 Springer Science+Business Med
描述Leading gene therapy researchers and clinicians illuminate the field-from basic vector technology to current and future clinical applications in neurology. The authoritative contributors provide cutting-edge reviews of the vectors available for gene transfer to the central nervous system, the strategies against CNS tumors, the potentialstrategies against neurologic disorder, and the limitations of today‘s gene therapy approaches.Also discussed are significant applications of gene therapy to brain tumors, Parkinson‘s disease, ischemia, and Huntington‘s chorea. Readers will learn the current delivery methods for transgenes, will learn the characteristics of transgene delivery vectors, and come to understand the therapy for both neuro-oncologic and neurologic disorders. ..
出版日期Book 1998
关键词Bur; Nervous System; Neurology; Parkinson; Promoter; genes; neurons; surgery
版次1
doihttps://doi.org/10.1007/978-1-59259-478-8
isbn_softcover978-1-4757-5314-1
isbn_ebook978-1-59259-478-8
copyrightSpringer Science+Business Media New York 1998
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https://doi.org/10.1007/978-3-319-72850-6rly (IE), early, and late. The latent infection occurs in sensory ganglia and is characterized by a complete absence of lytic gene expression but for the synthesis of a set of transcripts (of unclear function) referred to as the latency-associated transcripts (LATs). The potential applications for a
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https://doi.org/10.1007/978-3-319-63290-2rapy. It includes an overview of the general properties of transcriptional regulation, an analysis of the mechanisms by which cell-specific gene expression is achieved by interactions between promoters, transcription factors, chromatin, and methylation, and summarizes transgenic studies of brain-spe
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Simone Schönfeld,Nadja Tschirnerto take advantage of the underlying genetic abnormalities of tumor cells, those that contribute to the unregulated growth of cancer cells, prevent apoptosis, activate angiogenic factors, induce proliferation, and promote invasiveness. One of the most promising new therapeutic approaches involves the
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Soziale Gruppierungen manipulieren,ments in the context of the appropriateness of the experimental model may produce misleading conclusions that could delay the rational development of efficacious immunotherapeutic strategies. In the second part of this chapter, the recent literature dealing with the use of cytokine gene transfer to
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Newcomer – die unbekannten Game Changer-oncology since the mid-1970s .. Druckrey ., Benda, Schmidek, Swenberg, and Koestner . and their associates reported that central nervous system tumors could be induced selectively and reproducibly in adult rats that had been given repeated, weekly, intravenous (iv) injections of N-methylnitrosourea
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