| 书目名称 | Gene Therapy for HIV and Chronic Infections |
| 编辑 | Ben Berkhout,Hildegund C.J. Ertl,Marc S. Weinberg |
| 视频video | |
| 概述 | This book focuses on gene therapy and gene transfer approaches to prevent or treat chronoic virus infections.Discusses a collection of molecular antiviral strategies (ribozymes, RNAi, RNAu, aptamers, |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990’s. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous |
| 出版日期 | Book 2015 |
| 关键词 | HIV; chronic infections; gene therapy; gene transfer approaches; hepatitis |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4939-2432-5 |
| isbn_softcover | 978-1-4939-4865-9 |
| isbn_ebook | 978-1-4939-2432-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | American Society of Gene and Cell Therapy 2015 |
发表于 2025-3-21 18:21:21
