| 书目名称 | Gene Therapy for Autoimmune and Inflammatory Diseases |
| 编辑 | Yuti Chernajovsky,Paul D. Robbins |
| 视频video | |
| 丛书名称 | Milestones in Drug Therapy |
| 图书封面 |  |
| 描述 | In this monograph about gene therapy of autoimmune and inflammatory d- orders we have gathered international experts and leaders from different fields to review the state of the art advances on topics ranging from disease entities to vectors and engineered cells. The different approaches described in each chapter take into consideration the biomedical knowledge of these diseases and address the complexities of delivering long-term genetic interventions. Gene therapy also serves as a testing ground for new therapeutic entities and helps provide proof of principle for their potential therapeutic role in animal models of disease. Scaling up from mice to men still remains an important h- dle not only from the quantitative point of view, but also for currently unknown and unexpected secondary effects of the vector or the transgene. Some of these approaches have already been tested in the clinic, but much more needs to be done to understand the human conditions treated and the n- ural history of their pathology. We are indebted to the secretarial assistance of Ms. Lin Wells (Bone and Joint Research Unit, London, UK) and the help of Hans Detlef Klüber for his help in getting this book pub |
| 出版日期 | Book 2010 |
| 关键词 | Arthritis; Autoimmune Diseases; DNA; Immunology; Inflammatory Diseases; Promoter; gene therapy; genes |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-0346-0165-8 |
| isbn_softcover | 978-3-0348-0306-9 |
| isbn_ebook | 978-3-0346-0165-8Series ISSN 2296-6056 Series E-ISSN 2296-6064 |
| issn_series | 2296-6056 |
| copyright | Birkhäuser Basel 2010 |
发表于 2025-3-21 19:16:06
