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Titlebook: Gene Therapy for Acute and Acquired Diseases; Phillip Factor Book 2001 Kluwer Academic Publishers 2001 HIV.Trauma.gene therapy.gene transf

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发表于 2025-3-21 19:35:34 | 显示全部楼层 |阅读模式
书目名称Gene Therapy for Acute and Acquired Diseases
编辑Phillip Factor
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图书封面Titlebook: Gene Therapy for Acute and Acquired Diseases;  Phillip Factor Book 2001 Kluwer Academic Publishers 2001 HIV.Trauma.gene therapy.gene transf
描述In recent years much enthusiasm and energy has been directedtoward the development of human gene therapies, especially forinherited conditions and cancers. However, current gene transfertechnology is limited in its transduction efficiency and ability topermanently and safely correct genomic defects. Thus the promise ofgene therapy for these conditions is as yet unrealized. Theprogression of gene transfer technology will eventually surmount theselimitations...Gene Therapy for Acute and Acquired Diseases. includes selectedexamples of ongoing studies in molecular genetics that have thepotential to evolve into human therapies for acute illnesses. Thesechapters are intended to highlight lesser known applications of genetherapy for acquired disorders. It is expected that human gene therapytrials for these conditions will be forthcoming in the near future,leading to previously unimaginable therapies. Thus, this first-everbook about gene therapy for acute and acquired diseases is intended toserve as a glimpse into the future.
出版日期Book 2001
关键词HIV; Trauma; gene therapy; gene transfer; genes; genetics; infection; infections; infectious; infectious dise
版次1
doihttps://doi.org/10.1007/978-1-4615-1667-5
isbn_softcover978-1-4613-5668-4
isbn_ebook978-1-4615-1667-5
copyrightKluwer Academic Publishers 2001
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发表于 2025-3-21 21:49:35 | 显示全部楼层
Gene Delivery in the ICU,h inflammatory mechanisms may modulate the acute inflammation accompanying many critical illnesses. Similarly, transgene expression that restores production of crucial biological mediators affected by the acute illness may be beneficial. Transgene expression need also not be limited to naturally occ
发表于 2025-3-22 01:15:57 | 显示全部楼层
Non-Viral Gene Therapy for Pulmonary Disease, administration of formulations comprising DNA and lipid, proteins, peptides or polymers. While the main limitation of non-viral gene transfer methods is their relatively low efficiency ., both preclinical and clinical studies indicate that these methods exhibit safety profiles similar to convention
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Gene Therapy for Acute Lung Injury, Injury to the alveolar-capillary barrier and lung inflammation lead to intrapulmonary shunting of blood, surfactant depletion, and pulmonary vascular obstruction. Although the exact incidence of ARDS is unknown, there is little doubt that tens of thousands of patients develop this syndrome annually
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Gene Therapy for Preservation of Alveolar Endothelial and Epithelial Function,racellular adhesion molecules. More recently, it has been recognized that other alveolar proteins (e.g. antioxidants, solute transport or surfactant proteins) may also be compromised in ALI. Up to now, no avenues existed to restore the function of these proteins. Gene therapy and its potential to in
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Gene Therapy for HIV and AIDS-Related Opportunistic Infections, recessive fashion and carry a significant morbidity, such as Cystic Fibrosis. However, as the field has expanded, it has taken advantage of the increasing knowledge base that there are genetic components to acquired disorders such as cancer, HIV infection and other infectious diseases. For example,
发表于 2025-3-23 06:14:59 | 显示全部楼层
Gene Therapy for Acute Kidney Diseases,onary hemorrhage. The incidence of acute renal failure is 5% of hospital admissions and 30% of intensive care unit patients (.). The incidence of ARF has not decreased over the past two decades despite improvement of diagnostic methods and advances in supportive care. While the survival from isolate
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