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Titlebook: Gene Therapy and Cell Therapy Through the Liver; Current Aspects and Shuji Terai,Takeshi Suda Book 2016 Springer Japan 2016 CPC Isolator.a

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发表于 2025-3-21 16:44:43 | 显示全部楼层 |阅读模式
书目名称Gene Therapy and Cell Therapy Through the Liver
副标题Current Aspects and
编辑Shuji Terai,Takeshi Suda
视频video
概述Provides extensive information for examining the wide varieties of pathological conditions both inside and outside the liver.Focuses on cell therapy, gene therapy, and legal regulation of the applicat
图书封面Titlebook: Gene Therapy and Cell Therapy Through the Liver; Current Aspects and  Shuji Terai,Takeshi Suda Book 2016 Springer Japan 2016 CPC Isolator.a
描述.This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies. Edited by pioneering researchers, this volume presents extensive information to principal investigators, researchers, postdocs and clinicians for examining the wide varieties of pathological conditions both inside and outside the liver..Providing not only the basic and clinical aspects of therapy, this volume is special in that it focuses on the administrative and regulatory difficulties of actual clinical application and legal regulations in different parts of the globe. By indicating the advantages and limitations of the most promising gene and cell therapies targeting the liver, this book will inspire readers to develop a feasible treatment in the next generation.
出版日期Book 2016
关键词CPC Isolator; adeno-associated virus (AAV); immunotherapy; legal regulation; liver fibrosis; regeneration
版次1
doihttps://doi.org/10.1007/978-4-431-55666-4
isbn_softcover978-4-431-56251-1
isbn_ebook978-4-431-55666-4
copyrightSpringer Japan 2016
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Macrophage Therapy for Liver Fibrosis and Regenerationjury both the resident macrophages and circulating monocytes influence both liver regeneration and liver fibrosis. Kupffer cells can stimulate hepatocyte proliferation via the secretion of IL-6; macrophages stimulate a ductular proliferation via TWEAK secretion and also secrete Wnts which stimulate
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Novel Immunotherapy Using Liver-Derived Natural Killer Cells for Preventing Hepatocellular Carcinomaants. However, no prevention or treatment exists for HCC recurrence after liver transplantation. Here, we describe an adoptive immunotherapy approach that uses natural killer (NK) cells derived from both living and deceased donor liver graft perfusates. Liver NK cells exhibited the vigorous cytotoxi
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Potential Usage of Human Artificial Chromosome for Regenerative Medicineneered creation) or a “bottom-up approach” (de novo creation). HACs with one or more acceptor sites exhibit several characteristics required by an ideal gene delivery vector, including stable episomal maintenance and the capacity to carry large genomic loci plus their regulatory elements, thus allow
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Image-Guided Hydrodynamic Gene Delivery to the Liver: Toward Clinical Applicationsn its cells. Conventional therapeutic methods are often insufficient or unavailable to manage genetic diseases in the liver; therefore, more efficient strategies are urgently needed. Gene therapy emerged as novel method of treatment relying on liver-directed transfer of a gene-coding sequence to pro
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