Titlebook: Gene Therapy; Kleanthis G. Xanthopoulos Conference proceedings 1998 Springer-Verlag Berlin Heidelberg 1998 Genexpression.Krankheit.Krebs.M

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https://doi.org/10.1057/978-1-137-54000-3use at present to . procedures. One of the ultimate challenges for gene therapy will be to develop a vehicle for gene delivery that can be used .. The vector of choice is likely to remain a retrovirus; one of its major advantages being that it can link therapeutic sequences to the host chromosome wi

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https://doi.org/10.1007/978-1-137-06009-9ntry into cells. This domain is an anti-parallel ß sandwich with two helical subdomains forming loops adjacent to the ß-sandwich. The loops contains the determinants involved in receptor recognition. A purified 208 aminoacid fragment containing the amphotropic receptor binding domain competes with t

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Pranab Kumar Panday,Shuvra Chowdhuryopolitan US clinics. The common denominator appeared to be blood borne transmission of a virus as this patient group mostly comprised recipients of blood products (eg. factor VIII) and sexually active homosexual men. In 1983, a novel human retrovirus was isolated (2, 18, 24) and eventually named hum

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The First Decade of the New Millenniumally around 20 nm in diameter and are extremely resistant to a variety of harsh physical conditions (low pH, heat, presence of detergent). Within this family, Dependoviruses where first identified as contaminants of human adenovirus preparations and shown to be strictly dependent on the presence of

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Making Sense of Citizen Involvement,ducing genetic knock-outs in mice through the use of embryonic stem cells allowed the conception of efficient targeting in mammalian cells to become a distinct possibility. The availability of cloned genes and DNA sequences, combined with the ability to transfer and express genes in mammalian cells,

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G. Anthony Giannoumis,Nidhi Jonejan experimental settings imply variable chemical, physical, mechanical and biological tools, only a few of them are practically useful for human gene therapy applications. Each technique offers unique advantages and suffers from some problems, and the development of a vector combining all the strong

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Citizen-Consumers and Evolutionors are gaining increasing interest [1]. Progress has been made in the understanding how individual activities of viruses can be mimicked and methodologies have been developed which allow to combine different functions required for gene transfer into an artificial complex. An attractive approach for