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Titlebook: Gene Regulation by Steroid Hormones IV; Arun K. Roy,James H. Clark Conference proceedings 1989 Springer-Verlag New York, Inc. 1989 DNA.EGF

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Modulation of Glucocorticoid-Induced Responses by Cyclic AMP in Lymphoid Cell Lines,nd Lippman, 1974). The lytic process is dependent upon continued RNA and protein synthesis, and may represent induced transcription of one or more specific genes whose expression leads to programmed cell death (Munck and Crabtree, 1981; Young et al., 1980). Evidence for the existence of “lysis gene(
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Steroid Response Elements. Definition of a Minimal Promoter and Interaction with Other Activating S the various steroid hormones ishighly specific. It is mediated by binding of the hormone to its specific receptor which, after binding, attains the capacity to recognize a specific DNA region on regulated genes. This receptor-DNA interaction eventually leads in a still-unknown way to an increase of
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GHF-1, a Tissue-Specific Transcription Factor, is a Homeobox Protein, that the difference between GH gene activity in somatotropes and hepatocytes exceeds 10.-fold (Ivarie et al, 1983). To achieve this level of control, a highly specific mechanism should restrict GH expression to the correct cell type. The GH-expressing somatotrope is derived from an acidophylic stem
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Regulation of EGF Receptors and Nuclear Protooncogenes by Estrogen,sed the possibility that these growth responses may involve an interplay between the steroid, peptide growth factors, and nuclear protooncogenes. For example, estrogens stimulate secretion of IGF and EGF-like peptides in MCF-7 human breast cancer cells, and these peptides can support MCF-7 cell grow
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Regulation of the Rat Insulin II Gene: ,- and , Factors, has broad impact on the society. Aside from its medical importance, the insulin gene is interesting because it is specifically expressed in the β-cells of the islets of Langerhans in the pancreas, and this tissue-specificity is at the transcriptional level. Therefore, the insulin gene serves as a g
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Androgen Action in Rat Liver: Changes in Androgen Sensitivity During Maturation and Aging,ammals, it is also responsible for maintaining the sexually dimorphic pattern of steroid metabolism (Roy & Chatterjee, 1983; Gustafsson et al, 1983). A large number of studies investigating the effect of estrogens on the hepatic synthesis of vitellogenins have provided considerable understanding of
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