Titlebook: Gene Regulation by Steroid Hormones; Arun K. Roy (Professor of Biological Sciences),Jam Conference proceedings 1980 Springer-Verlag New Yo

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The Structure and Regulation of the Natural Chicken Ovomucoid GeneOne particularly attractive model system for studying this hormonal regulation has been the hen oviduct (O’Malley et al. 1969). A number of laboratories, in addition to our own, have utilized this model system for investigations of eucaryotic molecular biology (Oka and Schimke 1969; Palmiter and Sch

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The Effect of Estrogen on Gene Expression in Avian Livermething about regulation in eukaryotic cells. We were guided in this search by the following considerations. First, we did not want to work with a system in which cellular differentiation was itself an integral part of the regulatory response. We felt that we could obtain more clear-cut information

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Steroid Receptor Subunit Structureas been the chicken oviduct progesterone receptor (for reviews, see Schrader and O’Malley 1978; Vedeckis .. 1978). This receptor has been purified to apparent homogeneity and found to consist of two nonidentical progesterone-binding components. One, progestophilin A, has a molecular weight of 79 000

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Multiple Actions of Glucocorticoids Studied in Cell Culture Systemslogists for some time until the unifying concept of steroid- and tissue-specific receptors provided a means of recognizing those cells likely to respond (Thompson and Lippman 1974; King and Mainwaring 1974; Yamamoto and Alberts 1976). This clearing in the mystery, however, has proved to be more valu