Titlebook: Gene Regulation by Steroid Hormones; Arun K. Roy (Professor of Biological Sciences),Jam Conference proceedings 1980 Springer-Verlag New Yo

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Steroid Receptor Subunit Structure aggregates of these proteins (Schrader et al. 1975), crosslinking studies (Bimbaumer et al. 1979), and functional tests of chromatin transcription (Buller et al. 1976) have led to the belief that A and B are subunits of a larger AB complex.

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978-1-4612-6056-1Springer-Verlag New York Inc. 1980

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Chromatography and spectroscopic techniques,One particularly attractive model system for studying this hormonal regulation has been the hen oviduct (O’Malley et al. 1969). A number of laboratories, in addition to our own, have utilized this model system for investigations of eucaryotic molecular biology (Oka and Schimke 1969; Palmiter and Sch

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E. D. Morgan,H.-P. Huang,I. D. Wilsonas been the chicken oviduct progesterone receptor (for reviews, see Schrader and O’Malley 1978; Vedeckis .. 1978). This receptor has been purified to apparent homogeneity and found to consist of two nonidentical progesterone-binding components. One, progestophilin A, has a molecular weight of 79 000

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https://doi.org/10.1007/978-3-642-01656-1 and Ringold 1971 ; Erdos et al. 1969; Michel et al. 1974; Puca et al. 1971 ; Sanborn et al. 1971; Steggles and King 1970). One of these sites, the estrogen receptor, has been intensively investigated (Baulieu et al. 1975; Clark et al. 1978a; Gorski and Gannon 1976; Jensen et al. 1974; O’Malley and