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Titlebook: Gene Interactions in Development; L. I. Korochkin,A. Grossman Book 1981 Springer-Verlag Berlin � Heidelberg 1981 Embryo.Interactions.Molek

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书目名称Gene Interactions in Development
编辑L. I. Korochkin,A. Grossman
视频video
丛书名称Monographs on Theoretical and Applied Genetics
图书封面Titlebook: Gene Interactions in Development;  L. I. Korochkin,A. Grossman Book 1981 Springer-Verlag Berlin � Heidelberg 1981 Embryo.Interactions.Molek
描述Since the Russian edition of this book was published in 1975 many new research works have appeared which have made necessary some additions for the English edition, to reflect progress in molecular developmental genetics. Recent important findings in this field have brought about essential corrections to the concept of genetic regulation of the process of cell differentiation. The discovery of the mosaic structure of a gene prompted the re­ evaluation of our considerations about the regulation of gene activity in eukaryotes, and the data about transcriptional events during ontogenesis are of great importance as well. Formerly it was generally accepted that a derepression of genes was responsible for cell differentiation in the process of develop­ ment. Recently three important conclusions have been derived (Davidson and Britten, 1979) which help to pose the problem in a new way: 1) Only a small part of single copy sequences of DNA is represented in nuclear RNA of a given type of cell or tissue: 10% to 20% in sea urchin embryos, 11 % in rat liver, 4% to 6% in Drosophila cell culture, etc. Since only about 10% of single copy sequences represent the structural genes (Davidson and Brit
出版日期Book 1981
关键词Embryo; Interactions; Molekulargenetik; Ontogenie; development; ontogenesis; regulation; tissue; transcripti
版次1
doihttps://doi.org/10.1007/978-3-642-81477-8
isbn_softcover978-3-642-81479-2
isbn_ebook978-3-642-81477-8Series ISSN 0341-5376
issn_series 0341-5376
copyrightSpringer-Verlag Berlin � Heidelberg 1981
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Nuclear-Cytoplasmic Interactions. The Basis for the Regulation of Gene Activityentiation depends upon the nature of the cytoplasm in various parts of the egg (Lehman, 1957; Briggs and King, 1959; Nikitina, 1964). Cytoplasm heterogeneity first appears during oogenesis as a result of the process designated ooplasmic segregation. The essence of this process is the formation of eg
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g polarity and the animal-vegetative (and in many animals, dorsal-ventral as well) gradient distribution of active biological compounds such as RNA‘s, proteins, etc. The animal part of the egg is characterized by a higher level of metabolism (Brachet, 1960, 1961; Raven, 1964).
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