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Titlebook: Gene Expression and Regulation; Jun Ma Book 2006Latest edition Springer-Verlag New York 2006 Activation.Arabidopsis thaliana.Chromatin.DNA

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发表于 2025-3-21 17:38:46 | 显示全部楼层 |阅读模式
书目名称Gene Expression and Regulation
编辑Jun Ma
视频video
概述Provides comprehensive coverage of the science of gene expression and regulation.Edited by an expert in the field.Concentrates on concepts and issues, rather than specific organisms or experimental ap
图书封面Titlebook: Gene Expression and Regulation;  Jun Ma Book 2006Latest edition Springer-Verlag New York 2006 Activation.Arabidopsis thaliana.Chromatin.DNA
描述All genes must be expressed to exhibit their biological activities. How genes are expressed and regulated is a central question in molecular biology and our knowledge in this area has been expanding enormously in recent years. The complexity of gene regulation is compounded by the fact that gene activities reach every comer of biology. Transcription is universally the first step toward expressing a gene. It is a highly regulated process. Understanding the molecular mechanisms of transcription regulation is of fiindamental importance. For protein-coding genes, post-transcriptional steps, including pre-mRNA processing, mRNA transport and translation, can also play important roles in regulating gene expression. To contain the scope of this book, we will focus primarily on RNA polymerase II transcription and regulation. We will explore not only the biochemical basis of transcription but also the biological consequences of, and biological influences on gene transcription. The book is composed of 35 individual review articles written by authorities in the field. The chapters are organized into five sections: The History, The Machinery, The Regulators, The Genome, and Special Topics. The
出版日期Book 2006Latest edition
关键词Activation; Arabidopsis thaliana; Chromatin; DNA; Jun Ma; RNA; regulation; tissue
版次1
doihttps://doi.org/10.1007/978-0-387-40049-5
copyrightSpringer-Verlag New York 2006
The information of publication is updating

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Xiaoquan Zhou,Jiangtao Bai,Guangsheng Geitiation of transcription and requires a host of accessory proteins, termed general transcription factors (GTFs), to commence basal level transcription dictated by the core promoter elements. The GTFs for pol II-mediated transcription include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. The transcr
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https://doi.org/10.1007/978-981-10-7422-6ted general transcription factors (GTFs), including TBP, TFIIB, TFIIF, and TFIIH are sufficient for recognition and low levels of accurate transcription from common core promoter elements . (. and .). However, in addition to these factors necessary for basal transcription initiation, accurately regu
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China‘s Sustainability Transitionsily accessible to DNA binding transcription factors. Chromatin also provides the structural basis for gene regulation, keeping most genes in a default state of repression. The regulation of gene expression involves dynamic chromatin remodeling associated with reversible histone acetylation. The enzy
发表于 2025-3-22 17:03:49 | 显示全部楼层
pically found ∼40 bp upstream and downstream of the transcription start site, plays a crucial role in the recruitment and positioning of the basic transcription machinery. DNA elements within the core promoter can also control the levels of gene transcription and specify enhancer selectivity. These
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ytokines and growth factors to regulate transcription. Upon stimulation, STATs become tyrosine phosphorylated to form functional dimers. Activated STAT dimers then translocate into the nucleus where they directly bind to the promoters of downstream genes to activate transcription. Posttranslational
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ological activities, such as cell proliferation, differentiation, adhesion, migration, and apoptosis. The TGF-β family members signal through transmembrane serine/threonine kinase receptors. Smads are major intracellular mediators that transduce the TGF-β signal from the cell surface to the nucleus.
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