| 书目名称 | Gene Expression and Its Discontents | | 副标题 | The Social Productio | | 编辑 | Rodrick Wallace,Deborah Wallace | | 视频video | | | 概述 | Illustrates the significant implications for epigenetic epidemiology, in particular for understanding how environmental stressors, in a large sense, can induce a broad spectrum of developmental disord | | 图书封面 |  | | 描述 | .This book describes how epigenetic context, in a large sense, affects gene expression and the development of an organism, using the asymptotic limit theorems of information theory to construct statistical models useful in data analysis. The approach allows deep understanding of how embedding context affects development. We find that epigenetic information sources act as tunable catalysts, directing ontogeny into characteristic pathways, a perspective having important implications for epigenetic epidemiology. In sum, environmental stressors can induce a broad spectrum of developmental dysfunctions, and the book explores a number of pandemic chronic diseases, using U.S. data at different scales and levels of organization. In particular, we find the legacy of slavery has been grossly compounded by accelerating industrial decline and urban decay. Individual chapters are dedicated to obesity and its sequelae, coronary heart disease, cancer, mental disorders, autoimmune dysfunction, Alzheimer’s disease, and other conditions. Developmental disorders are driven by environmental factors channeled by historical trajectory and are unlikely to respond to medical interventions at the populatio | | 出版日期 | Book 2016Latest edition | | 关键词 | AIDS; Cancer; Epidemiology; Obesity; gene expression; genes; genetic epidemiology | | 版次 | 2 | | doi | https://doi.org/10.1007/978-3-319-48078-7 | | isbn_softcover | 978-3-319-83893-9 | | isbn_ebook | 978-3-319-48078-7 | | copyright | Springer International Publishing Switzerland 2016 |
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发表于 2025-3-21 17:07:55
