Titlebook: Gene Expression Systems in Fungi: Advancements and Applications; Monika Schmoll,Christoph Dattenböck Book 2016 Springer International Publ

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https://doi.org/10.1057/9780230599284ngi as hosts for protein production in structural biology is questioned. We also discuss the emerging opportunities offered by the complementary fields of systems biology and synthetic biology, which might open new possibilities for successful heterologous protein production in fungi.

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ation of novel molecules. Interestingly, even the addition of bacterial molecules such as lipopolysaccharide was apparently sufficient to trigger a response of the fungal partner. Another successful approach is to delete, overexpress or inhibit histone-modifying enzymes/genes. In line, approaches ta

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Fernando Jorge Portela Martins Ascensãoalvage their lignocellulolytic enzymes. . is a prominent producer of penicillin N and can also produce carbohydrate active enzymes (CAZYs). Many involved genes are under the negative control of CreA/1 and repressed by it in presence of .-glucose. Exploiting CCR for protein production means to find a

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el organism for studies on cellulose degradation and its cellulase enzyme complex since the 1940s, which suggested its use for industrial bioethanol manufacturing during the oil crisis in the mid 1970s. Extensive strain development campaigns by different laboratories proved that the wild type isolat

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rge amounts of enzymes for lignocellulose deconstruction that release fermentable sugars from the plant cell walls. The most commonly used fungi for this purpose are . and several .. However, the saprophytic ascomycete . has already made undeniable contributions to fundamental science in the past, a

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