| 书目名称 | Gene Essentiality | | 副标题 | Methods and Protocol | | 编辑 | Long Jason Lu | | 视频video | | | 概述 | Includes cutting-edge methods and protocols for the study of microbial gene essentiality.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice fr | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .This volume opens by covering two main types of approaches widely used to determine essential genes: single-gene knockouts and transposon mutagenesis, in both prokaryotes and .Candida albicans.. Given the significant advancement in the computational predictions of microbial essential genes, the second half of the book examines four main types of approaches: comparative genomics, supervised machine learning, constraint-based methods, and corrections of transposon mutagenesis data, as well as databases and servers that are often used in studying gene essentiality. Written in the highly successful .Methods in Molecular Biology. series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and up-to-date, .Gene Essentiality: Methods and Protocols. will aid researchers who wish to further our knowledge in this vital field of study.. | | 出版日期 | Book 2015 | | 关键词 | Candida albicans; Computational predictions; Microbial essential genes; Prokaryotes; Single-gene knockou | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-2398-4 | | isbn_softcover | 978-1-4939-4862-8 | | isbn_ebook | 978-1-4939-2398-4Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 2015 |
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发表于 2025-3-21 17:22:04
