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Titlebook: GeNeDis 2014; Geriatrics Panayiotis Vlamos,Athanasios Alexiou Conference proceedings 2015 The Editor(s) (if applicable) and The Author(s),

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https://doi.org/10.1007/978-3-030-51633-8the twenty-first century. Approved drugs for dementia exhibit moderate efficacy and offer temporary improvement to patients. Caregivers and medical professionals have been searching for more effective interventions.
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Non-pharmacological Treatments for People with Dementia,the twenty-first century. Approved drugs for dementia exhibit moderate efficacy and offer temporary improvement to patients. Caregivers and medical professionals have been searching for more effective interventions.
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Searching for AD-Related Biological Vulnerability in Cognitively Intact People: A New Perspective fing neuropathological, cellular, and molecular substrates of Alzheimer disease (AD). The concept of AD pathogenesis has evolved from a static, binary view discriminating cognitive normality from dementia towards a dynamic view that considers AD pathology as a long-lasting morbid process that takes p
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Proteasome Activation Delays Aging and Protects Against Proteotoxicity in Neurodegenerative Diseaseon in replicative senescence and cell survival (Mol Aspects Med, in press, 2013). We have observed reduced levels of proteasome content and activities in senescent cells due to the downregulation of the catalytic subunits of the 20S complex (J Biol Chem 278, 28026–28037, 2003). In support, partial i
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Neuropathological Changes in Aging Brain,s that assessed the relationship of cognitive decline with neuropathologic lesions, their correlation still remains unclear. NFTs and Aβ plaques have been widely implicated and described in normal aging. The number of NFTs in the CA1 and the entorhinal cortex seems to be more closely related to cogn
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