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Titlebook: Gastrointestinal Stromal Tumors; Bench to Bedside Charles R. Scoggins,Chandrajit P. Raut,John T. Mul Book 2017 Springer International Publi

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,Der Atomismus der Elektrizität,ogic outcomes compared to open resection [1–8]. However, as with any operation for GIST, the adherence to oncologic surgical practices, including prevention of tumor spillage and appropriate resection, must be considered before deciding on a minimally invasive resection [1].
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,Die künstliche Atomumwandlung,6, 2001), traditional chemotherapy agents failed usually causing stable disease at best without improvement of progression-free or overall survival (OS) (Edmonson et al., Cancer Invest 20(5–6):605–612, 2002; Blay et al., Eur J Cancer 40(9):1327–1331, 2004; Trent et al., Cancer 98(12):2693–2699, 2003
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hotographs and illustrationsThis textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book  reviews new data about risk factors for the disease, profiles the new staging
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https://doi.org/10.1007/978-3-663-11966-1een improved based on recent molecular discoveries. The irruption of tyrosine kinase inhibitors in the field revolutionized the treatment of patients with GIST and became a paradigm of translational research in modern oncology. In this chapter, we would like to discuss the most recent advances in targeted therapy for patients with GIST.
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Folgen der Lungen- und Pleuraverletzungentreated on a clinical trial with imatinib, a tyrosine kinase receptor inhibitor of KIT. Today, imatinib is approved for use in advanced/metastatic GIST and as adjuvant therapy. Future advances require an understanding of the molecular biology of when imatinib is ineffective, which will open opportunities for new treatments.
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