书目名称 | Gastric Inhibitory Polypeptide | 编辑 | John Canvin Brown | 视频video | http://file.papertrans.cn/381/380828/380828.mp4 | 丛书名称 | Monographs on Endocrinology | 图书封面 |  | 描述 | Dr. Raymond Pederson, Dr. Jill Dryburgh and I commenced work on GIP in 1968, when, with the generous help of Professor Viktor Mutt and Professor Erik Jorpes of the Karolinska Inst,itute, Stockholm, we were able to establish that there existed an inhibitory material for acid secretion in cholecystokinin-pancreozymin prepara tions. Once the physiological evidence for the inhibitor was established it seemed appropriate to seek help in its isolation. Dr. J. Dryburgh and Dr. R. Pederson were left to bioassay fractions in Vancouver whilst I enjoyed the company of Professor Mutt at the Karolinska for one year, as a Medical Research Council of Canada Visiting Scientist. Purification of the inhibitory factor proceeded rapidly due, in no small measure, to Professor Mutt‘s untirmg efforts on my behalf. Later that year, Dr. Dryburgh joined us in Stockholm to begin the sequence work on GIP. This was completed late in 1970 in Vancouver. In Stockholm in June 1970, I met a fellow Canadian Dr. John Dupre (McGill University) at a cocktail party who kept commenting about the possibility of GIP being an insulinotropic hormone, the "incretin" of earlier days. At that time, gastrointestinal physiologis | 出版日期 | Book 1982 | 关键词 | Gastric inhibitory polypeptide; biosynthesis; cholecystokinin; diabetes; diabetes mellitus; glucagon; horm | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-81771-7 | isbn_softcover | 978-3-642-81773-1 | isbn_ebook | 978-3-642-81771-7Series ISSN 0077-1015 | issn_series | 0077-1015 | copyright | Springer-Verlag Berlin, Heidelberg 1982 |
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