| 书目名称 | Gasotransmitters in Organ Transplantation | | 副标题 | A New Era in Transpl | | 编辑 | George J. Dugbartey | | 视频video | | | 概述 | Provides the beneficial effects of gasotransmitters in organ transplantation.Presents a novel but simpler, safer and more cost-effective approach to organ preservation and transplantation.Discusses cl | | 图书封面 |  | | 描述 | .This book covers recent pre-clinical and clinical developments in gasotransmitters (nitric oxide, carbon monoxide and hydrogen sulfide) in all transplantable solid organs – kidney, heart, lung, liver, pancreas and intestine. Gasotransmitters are a class of small endogenously produced gaseous signaling molecules that play important roles in cellular homeostasis and impact physiological and pathophysiological situations. Recently, these gasotransmitters have emerged as potent cytoprotective mediators, possessing therapeutic properties that enable them exhibit their intracellular signaling functions. Hence, alterations in their physiological levels have been associated with various pathologies including cold ischemia-reperfusion injury (IRI) in organ transplantation. .In the context of organ transplantation, a novel therapeutic strategy that is being investigated involves administration of these gasotransmitters to the organ donor or recipient before or after transplantation, or supplementation of standard preservation solution with gasotransmitters during organ graft preservation to mitigate transplant-induced IRI. The book is divided into three parts for easier access: .Hydrogen Su | | 出版日期 | Book 2024 | | 关键词 | Organ transplantation; Gasotransmitters; ischemia-reperfusion injury; transplantable solid organs; Organ | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-031-48067-6 | | isbn_softcover | 978-3-031-48069-0 | | isbn_ebook | 978-3-031-48067-6 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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发表于 2025-3-21 16:41:32
