书目名称 | Gapmers |
副标题 | Methods and Protocol |
编辑 | Toshifumi Yokota,Rika Maruyama |
视频video | |
概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | .This volume presents a comprehensive collection of detailed state-of-the-art protocols for gapmer-mediated RNA knockdown from leaders in the field. Chapters detail a historical and contemporary perspective of RNase H-inducing antisense oligonucleotides called gapmers and gapmer-mediated RNA knockdown for basic research and therapies. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls... Authoritative and cutting-edge, .Gapmers: Methods and Protocols. aims to provide diverse applications of gapmers along with protocols that will assist readers in moving the frontier.. |
出版日期 | Book 2020 |
关键词 | Antisense oligonucleotides; Gene silencing; Drug development; Gapmer therapeutics; Gapmer-mediated degra |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-0716-0771-8 |
isbn_softcover | 978-1-0716-0773-2 |
isbn_ebook | 978-1-0716-0771-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science+Business Media, LLC, part of Springer Nature 2020 |