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Titlebook: Gangliosides and Neuronal Plasticity; Guido Tettamanti,Robert W. Ledeen,Gino Toffano Book 1986 Springer-Verlag Berlin Heidelberg 1986 Germ

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Ganglioside-Mediated Modulation of Growth Factor Receptor Functionay an important role in cell-cell recognition (cell social function), while the other class is composed of a few basic structures, such as GM3, lactosylceramide, and glucosylceramide, common to many types of cells. The latter class of glycosphingolipids and even some of the former class may play a b
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Functional Analysis of Ganglioside-Respondable Human Neuroblastoma Cell Linesneurite length in a highly specific manner in two human neuroblastoma cell lines, GOTO and NB-1. As little as a few nanomolar concentration of GQlb was sufficiently effective. Our subsequent analysis of the structure and activity relationship using various gangliosides revealed an interesting fact t
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Rainer Müller,Ali Kanso,Fabian Adlerand Suzuki, 1976) prior to neuronal death and this has led to much of the current interest in gangliosides as neuritogenic agents. Much of this Symposium will be devoted to the stimulatory, neurite regenerative capacity of gangliosides, so it is important to remember the neuropathological origins of the “ganglioside effect”.
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On Measurement, Methodology and Systems, sciatic nerve of rabbit (Yates et al., 1984) and rat (Aquino et al., 1985a) have demonstrated similar anterograde flow of gangliosides in the PNS as well. The above rat system, involving motoneurons, also revealed another aspect of ganglioside movement in the neuron, i.e., retrograde axonal transport.
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Psychology and Philosophy of Science,gents with an inhibiting influence. To seek and investigate a beneficial (promoting) agent one must rely on restrictive circumstances, either imposed experimentally or occuring naturally as may be the case in developmental or pathological situations.
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Advances in Ganglioside Chemistrye moiety and the external ligand (Brady and Fishman, 1979; Holmgren et al., 1980). The hydrophobic portion is inserted into the lipid layer of the membrane and might participate in the process of signal transduction through the membrane (Brady and Fishman, 1979).
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