书目名称 | Galenics of Insulin | 副标题 | The Physico-chemical | 编辑 | Jens Brange | 视频video | | 图书封面 |  | 描述 | Galenical pharmacy or galenics is the science dealing with the pro duction of drug substances from raw materials, the purity of such substances, their formulation into pharmaceutical preparations with the desired effects and safety in use, and the quality control, stability and storage of the preparations. The field has taken its name from the Greek physician Galen (131-201 A.D.), who had a profound influence on medicine for many centuries because he collected and systematized the medicinal knowledge of his time. The discovery of insulin is attributed to Banting and Best who, in 1921, prepared an extract of the pancreas of the fetal calf and showed that the extract was capable of reducing the blood sugar level of a diabetic dog. This outstanding discovery gave rise to the rapid develop ment of the manufacture of insulin of bovine and porcine origin. By 1925, two Danish manufacturers of insulin preparations were established; both have since been in the forefront ofthe development of insulin preparations, the latest achievement being the marketing of human insulin by Novo in 1982. The development of highly purified human insulin produced semisynthetically from porcine insulin or by | 出版日期 | Book 1987 | 关键词 | DNA; Insulin; chemistry; chromatography; drug; immunology; pharmaceutical chemistry; production; standardiza | 版次 | 1 | doi | https://doi.org/10.1007/978-3-662-02526-0 | isbn_softcover | 978-3-662-02528-4 | isbn_ebook | 978-3-662-02526-0 | copyright | Springer-Verlag Berlin Heidelberg 1987 |
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