| 书目名称 | Gadd45 Stress Sensor Genes |
| 编辑 | M. Raza Zaidi,Dan A. Liebermann |
| 视频video | |
| 概述 | Provides a comprehensive picture of the unique global role Gadd45 genes plays.Interest in Gadd45 stress signaling is exponentially increasing.Gadd45 stress signaling modulate a wide range of normal & |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | .This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors..The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation.. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45proteins play as stress sensors and the molecular pathways involved.. |
| 出版日期 | Book 2022Latest edition |
| 关键词 | gene function; proteins; stress sensors; stress signaling; cancer; innate immunity |
| 版次 | 2 |
| doi | https://doi.org/10.1007/978-3-030-94804-7 |
| isbn_softcover | 978-3-030-94806-1 |
| isbn_ebook | 978-3-030-94804-7Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:57:11
