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Titlebook: GTPases in Biology I; Burton F. Dickey,Lutz Birnbaumer Book 1993 Springer-Verlag Berlin Heidelberg 1993 Calcium.DNA.Nucleotide.RNA.biochem

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书目名称GTPases in Biology I
编辑Burton F. Dickey,Lutz Birnbaumer
视频video
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: GTPases in Biology I;  Burton F. Dickey,Lutz Birnbaumer Book 1993 Springer-Verlag Berlin Heidelberg 1993 Calcium.DNA.Nucleotide.RNA.biochem
描述Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches utilized intracellularly in biological systems. The origins of the GTPase switch appear to be almost as ancient as life itself, and through evolution nature has adapted this switch to a variety of purposes. In this two-volume work a broad survey of the major classes of GTPases is presented. The role of GTPases in ensuring accuracy during protein translation, a new look at the trimeric G-protein cycle, the molecular function of ARF in vesicle coating, the emerging role of the dynamin family in vesicle transfer, GTPases which activate GTPases during nascent protein translocation, and the many roles of ras-related proteins in growth, cytoskeletal polymerization, and vesicle transfer, are all described in 80 chapters by the leading authorities in their fields. Both detailed knowledge of specific systems or proteins and general principles of structure and function are offered. Much of this information has never been published before. At the rate the extended family of GTPases is growing it becomes increasingly unlikely that we will again get it to sit for a group portrait s
出版日期Book 1993
关键词Calcium; DNA; Nucleotide; RNA; biochemistry; biology; gene expression; membrane transport; metabolism; molecu
版次1
doihttps://doi.org/10.1007/978-3-642-78267-1
isbn_softcover978-3-642-78269-5
isbn_ebook978-3-642-78267-1Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1993
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Small GTPases and Vesicle Trafficking: Sec4p and its Interaction with Up- and Downstream Elementser is generally mediated by vesicular transport. By this mechanism, a vesicle buds from a donor organelle and migrates through the cytoplasm until it recognizes the appropriate target organelle (. 1975; for a recent review see . and . 1992). The fusion of the vesicle membrane with that of the target
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Heterotrimeric G-Proteins: α, β, and γ Subunits α (39-52kDa), β (35-36 kDa), and γ (7-10 kDa). They are widely distributed among different tissues and organisms and their structures are highly conserved. This chapter briefly reviews the structure of the cDNAs and the genes for various G-protein α, β, and γ subunits from mammalian cells and the o
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