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Titlebook: GISTs - Gastrointestinal Stromal Tumors; Elisabetta Lutio di Castelguidone,Antonella Messin Book 2011 Springer Verlag Milan 2011 Gastroint

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Anatomic and Clinical Pathologyrs. The oncogenic drivers are tyrosine kinase enzymes (KIT) and, to a lesser degree, platelet- derived growth factor receptor alpha (PDGFRA), both of which become constitutively activated following certain primary mutations. These mutations are mostly in the . gene and rarely in ...The diagnosis rel
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Conventional Radiography-contrast barium studies of the gastrointestinal tract may, however, be useful (In occasional cases) In demonstrating direct and/or Indirect signs of GISTs..The radiological characteristics of this kind of tumor on conventional barium studies are often non-specific The tumor’s growth pattern may be
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Ultrasound, Color-Doppler Ultrasound and Contrast-enhanced Ultrasound of Primary GISTs and Liver Metors (GISTs). Although there are well-known limitations in the use of ultrasounds to scan the gastrointestinal tract, US can assess the primary site of growth of GISTs as well as their metastasis to the liven Gray-scale US, color-power-Doppler techniques, and contrast-enhanced US (CEUS) are all usefu
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Magnetic Resonanceance (MR). MR can be used In the Identification, characterization and staging of GISTs, as well as In the evaluation of response to treatment, showing the tissue changes Induced In cancer cells by molecular targeted therapies, Including myxohyaline changes, fibrosis, hemorrhagic necrosis and cellula
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