| 书目名称 | GAPDH: Biological Properties and Diversity |
| 编辑 | Norbert W. Seidler |
| 视频video | |
| 概述 | Provides a resource of ideas and references for biomedical researchers that are preparing grant applications.Contains a comprehensive synthesis of GAPDH information from widely-divergent fields.Provid |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | The book represents a comprehensive review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Due to the protein’s involvement in a vast array of cellular activities, GAPDH is of interest to the cell biologist, immunologist, virologist, biochemist etc. The protein has a significant role in fertility, cancer and neurodegeneration, suggesting that this book can be a vital resource for drug development. GAPDH function may provide insight into anesthesia. Furthermore, GAPDH is highly conserved meaning that the protein found in microorganisms, such as pathogens, remained relatively unchanged in evolution. Pathogens use GAPDH as a virulence factor, offering a unique challenge in developing anti-microbial agents that target this protein. To the evolutionary biologist, a book on the multi-functionality of GAPDH provides a focal point for a cogent discussion on the very origin of life. |
| 出版日期 | Book 2013 |
| 关键词 | apoptosis; cancer; glyceraldehyde 3-phosphate dehydrogenase; inhaled anesthetics; neurodegeneration |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-94-007-4716-6 |
| isbn_softcover | 978-94-024-0629-0 |
| isbn_ebook | 978-94-007-4716-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 201 |
发表于 2025-3-21 17:34:26
