Titlebook: GABAB Receptor; Giancarlo Colombo Book 20161st edition Springer International Publishing Switzerland 2016 GABA B receptor.Gastroesophageal

Assert

书目名称GABAB Receptor影响因子(影响力)




书目名称GABAB Receptor影响因子(影响力)学科排名




书目名称GABAB Receptor网络公开度




书目名称GABAB Receptor网络公开度学科排名




书目名称GABAB Receptor被引频次




书目名称GABAB Receptor被引频次学科排名




书目名称GABAB Receptor年度引用




书目名称GABAB Receptor年度引用学科排名




书目名称GABAB Receptor读者反馈




书目名称GABAB Receptor读者反馈学科排名

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过滤

https://doi.org/10.1007/978-3-476-02825-9 of mesolimbic circuits. Beyond a physiological role GABA. receptors may also affect disease, such as addiction. GABA. receptors may therefore constitute an interesting target for pharmacological interventions to treat this condition.

勉强

https://doi.org/10.1007/978-3-476-04308-5t GABA. receptor agonists and positive allosteric modulators may have efficacy in the treatment of SUD, with GABA. receptor positive allosteric modulators having a better pharmacological profile than orthosteric agonists. There is the need for additional clinical studies to ascertain whether preclinical data translate to the human.

DEAWL

osculate

The Allosteric Modulation of the GABAB Receptor: A Medicinal Chemistry Perspectivetural classes of GABA. allosteric modulators are described with an emphasis on structure–activity relationships (SAR) and synthesis of the main representatives of each class. Medicinal chemistry strategies to overcome issues related to allosteric modulators development are also discussed.

osculate

GABAB Receptor Functions in the Mesolimbic Dopamine System of mesolimbic circuits. Beyond a physiological role GABA. receptors may also affect disease, such as addiction. GABA. receptors may therefore constitute an interesting target for pharmacological interventions to treat this condition.

的阐明

Targeting the GABAB Receptor for the Treatment of Substance Use Disordert GABA. receptor agonists and positive allosteric modulators may have efficacy in the treatment of SUD, with GABA. receptor positive allosteric modulators having a better pharmacological profile than orthosteric agonists. There is the need for additional clinical studies to ascertain whether preclinical data translate to the human.

FELON

Targeting the GABAB Receptor for the Treatment of Alcohol Use DisorderA more recent avenue of research is represented by generalization of baclofen effects to the positive allosteric modulators of the GABA. receptor: preclinical data collected to date suggest that these compounds reproduce, with a much higher therapeutic index, several suppressing effects of baclofen on alcohol-motivated behaviors.

Grievance

1048-6909 nt perspectives from various fields of study including medic.An up-to-date comprehensive overview of the GABA B receptor system with a particular focus on the most recent therapeutic applications and potential. This receptor system has recently been implicated in several diseases and disorders inclu