| 书目名称 | G-Quadruplex DNA | | 副标题 | Methods and Protocol | | 编辑 | Peter Baumann | | 视频video | | | 概述 | Includes coverage of a wide range of methodologies to study G-quadruplex structures.Provides detailed protocols which ensure successful re-recreation of experimental procedures.Supplies step-by-step i | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .Recent work has revealed that stabilizing G-quadruplexes in telomeric DNA inhibits telomerase activity, providing impetus for the development of G-quartet-interacting drugs, while G-quartet-containing oligonucleotides have been recognized as a potent class of aptamers effective against STAT3 and other transcription factors implicated in oncogenesis, proving these guanine-quartets to be a vital and rich area for future study. In "G-Quadruplex DNA: Methods and Protocols", experts in the field present a collection of detailed techniques for studying G-quartet formation, dynamics, and molecular recognition. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls...Authoritative and cutting-edge, "G-Quadruplex DNA: Methods and Protocols "promises to be a useful resource for those familiar with G-quartets as well as an easy entry point for those researchers from diverse fields who are just developing an interest in the exciting implications of | | 出版日期 | Book 2010 | | 关键词 | DNA; Drug development; G-quartet formation and dynamics; Guanine bases; Molecular recognition; Oligonucle | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59745-363-9 | | isbn_softcover | 978-1-4939-5639-5 | | isbn_ebook | 978-1-59745-363-9Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Humana Press 2010 |
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发表于 2025-3-21 18:19:44
