Titlebook: G Proteins, Receptors, and Disease; Allen M. Spiegel (Chief, Metabolic Diseases Branch Book 1998 Springer Science+Business Media New York

行乞

Disorders with Increased or Decreased Responsiveness to Extracellular Ca2+ Owing to Mutations in th and enzymatic cofactor that coordinates and controls cellular processes as diverse as muscular contraction, secretion, and glycogen metabolism as well as cellular proliferation, differentiation, and motility .. The basal level of Ca. ., generally~100 n., is much lower than the extracellular ionized

biopsy

Stagger

Mutation of the Growth Hormone-Releasing Hormone Receptor in the little Mouse,ph cells to stimulate the synthesis and secretion of GH (.). The actions of GHRH are opposed by those of somatostatin, a peptide hormone of hypothalamic origin that acts to suppress pituitary growth hormone secretion; together, GHRH and somatostatin are thought to be the predominant mediators of the

祸害隐伏

Functional Variants of the MSH Receptor (MC1-R), Agouti, and Their Effects on Mammalian Pigmentatiohat plays an important role in the regulation of mammalian pigmentation. No diseases and in fact no pigmentation phenotypes in humans have been definitively linked to this receptor. Nevertheless, the study of the MC 1 -R has introduced at least two novel paradigms to the G-protein signaling field: f

Calibrate

ACTH Resistance Syndromes, has opened a new understanding of the normal and pathologic functioning of the adrenal cortex. This chapter will focus on the clinical forms of hereditary ACTH resistance syndromes and their association with abnormalities of the ACTH receptor gene.

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联邦

Dopamine Receptors in Human Disease,tems (.). In the central nervous system, dopamine affects locomotion and behavior. In the cardiovascular system, dopamine affects heart rate and myocardial contractility. Dopamine effects on blood pressure and blood volume have been postulated to involve both brainstem and direct renal mechanisms, a

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Limerick

Book 1998 how cells communicate via G-protein-coupled signal transduction processes, but also how defects in these proteins and their receptors can cause serious human disease involving many different organ systems. Written by leading investigators, each chapter describes in detail the structure and function

Desert

Social and Cultural World History theca cells to produce androgen precursors necessary for estrogen synthesis, and on the ovarian follicles to promote ovulation, subsequent corpus luteum formation, and progesterone secretion. Chorionic gonadotropin produced by the placenta acts on the corpus luteum and promotes development of the fetal testes in the first trimester of pregnancy.