| 书目名称 | G Protein-Coupled Receptors in Drug Discovery | | 副标题 | Methods and Protocol | | 编辑 | Marta Filizola | | 视频video | | | 概述 | Includes cutting-edge methods and protocols on GPCRs in drug discovery.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .This detailed volume provides an overview of recent techniques employed in the field of G protein-coupled receptors (GPCRs) to screen for new drugs and to derive information about their receptor structure, dynamics, and function for the purpose of developing improved therapeutics. Owing to remarkable recent advances in the structural, biophysical and biochemical analyses of these receptors, as well as a growing body of evidence hinting at the possible relevance of allosteric modulators, biased agonists and oligomer-selective ligands as improved therapeutic agents, drug discovery for GPCRs has recently taken a completely new direction. For this book, expert contributors have shared their protocols and views on the impact of these methodologies on modern drug discovery. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls..Practical and fully updated, .G Protein-Coupled Receptors in Drug Discovery: Methods and Protocols, Second Edition. serves as an | | 出版日期 | Book 2015Latest edition | | 关键词 | Allosteric modulators; Biased agonists; Drug design; Drug targets; GPCRs; Oligomer-selective ligands; Rece | | 版次 | 2 | | doi | https://doi.org/10.1007/978-1-4939-2914-6 | | isbn_softcover | 978-1-4939-4967-0 | | isbn_ebook | 978-1-4939-2914-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 2015 |
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发表于 2025-3-21 16:43:05
