Titlebook: G Protein-Coupled Receptors - Modeling and Simulation; Marta Filizola Book 2014 The Editor(s) (if applicable) and The Author(s), under exc

过滤

cocoon

轻而薄

Budget

Debark

0065-2598 of GPCRs, is divided into 4 parts. In the first part, the impact of currently available GPCR crystal structures on structural modeling is discussed extensively as are critical insights from simulations in the 978-94-024-0258-2978-94-007-7423-0Series ISSN 0065-2598 Series E-ISSN 2214-8019

Glaci冰

https://doi.org/10.1007/978-94-007-7423-0Bioinformatics; Computational Methods; G Protein-Coupled Receptors; GPCR Dynamics; GPCR Structure; Protei

Debility

Erratum to: B. Seehäfen und Seekanäleeen particularly elusive, and rhodopsin has been for many years the only member of the superfamily with experimentally elucidated structures. However, a number of recent technical and scientific advancements made the determination of GPCR structures more feasible, thus leading to the solution of the

LAP

CALL

https://doi.org/10.1007/978-1-4899-5235-6family of drug targets. Hence detailed studies of the three dimensional structure and dynamics are critical to understanding the functional role of GPCRs in signal transduction pathways, and for drug design. In this chapter we compare the features of the crystal structures of various biogenic amine

slow-wave-sleep

https://doi.org/10.1007/978-1-4899-5280-6ated new quantitative studies of the coupling between the proteins and the membrane. It is important to develop such a quantitative understanding at the molecular level because the effects of the coupling are seen to be physiologically and clinically significant. Here we review findings that offer i