书目名称 | G Protein Signaling Mechanisms in the Retina |
编辑 | Kirill A. Martemyanov,Alapakkam P. Sampath |
视频video | |
概述 | Includes descriptions of all GPCR-mediated signaling pathways in the retina that contribute to visual and circadian function.Brings together the most prominent experts in retinal biology, and it chall |
丛书名称 | Springer Series in Vision Research |
图书封面 |  |
描述 | The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light. The organization of this volume will generally follow the path of signal flow in the retina. First we will describe recent advances in understanding the phototransduction cascade of rod and cone photoreceptors, which use signaling cascade based on the GPCR rhodopsin to transduce incident light into neural activity. Chapters will be devoted to unique specializations of the two major types of photosensitive cells that comprise the predominant input for our spatial and color vision. Subsequently, the mechanisms of synaptic information encoding by retinal ON bipolar cells will be described, where the GPCR mGluR6 plays a fundamental role. Chapters in this section will examine macromolecular organization of the mGluR6 signaling pathway as well as current understanding of its function. The functional characteristics of this signaling mechanism will be explored in detail. Additionally, this section will cover the role of dopamine receptors in modu |
出版日期 | Book 2014 |
关键词 | G protein; GPCR; Retina; Signal transduction; vision; Receptors |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4939-1218-6 |
isbn_softcover | 978-1-4939-5506-0 |
isbn_ebook | 978-1-4939-1218-6Series ISSN 2625-2635 Series E-ISSN 2625-2643 |
issn_series | 2625-2635 |
copyright | Springer Science+Business Media New York 2014 |