| 书目名称 | Fundamentals of Pediatric Drug Dosing | | 编辑 | Iftekhar Mahmood,Gilbert Burckart | | 视频video | | | 概述 | Collects information on physiological, pharmacological, and pharmacokinetic differences between the pediatric population and adults, providing a comprehensive overview to the reader.Discusses the impo | | 图书封面 |  | | 描述 | .Focused on pediatric physiology, pharmacology, pharmacokinetics and pharmacodynamics, this book illustrates the differences between the pediatric population and adults; knowledge of extreme importance not only during pediatric drug development but also in the clinical practice. Physicians, nurses, clinical pharmacologists, researchers and healthcare professionals will find this an invaluable resource. .With the advent of pediatric exclusivity, and requirements to conduct clinical studies in children, an emphasis has been placed on finding a safe and efficacious dose of a drug in children. Children are not ‘small adults’, and drug dosing in this population requires special consideration. There are subtle physiological and biochemical differences among neonates, infants, children, adolescents and adults and dosing in pediatrics requires proper understanding of these factors. Furthermore, dosing in children, as in adults, should be based on pharmacokinetic and pharmacodynamic data. This is an evolving area, as pediatric pharmacokinetic studies are becoming mandatory for getting approval of new drugs in this population.. | | 出版日期 | Book 2016 | | 关键词 | Allometric Scaling; Clinical Pharmacology; Pediatric Clinical Trial; Pharmacokinetic Modeling; Pharmacok | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-43754-5 | | isbn_softcover | 978-3-319-82903-6 | | isbn_ebook | 978-3-319-43754-5 | | copyright | Springer International Publishing Switzerland 2016 |
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发表于 2025-3-21 16:11:49
