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Titlebook: Epigenome Editing; Methods and Protocol Albert Jeltsch,Marianne G. Rots Book 2024Latest edition The Editor(s) (if applicable) and The Autho

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发表于 2025-3-21 19:51:03 | 显示全部楼层 |阅读模式
书目名称Epigenome Editing
副标题Methods and Protocol
编辑Albert Jeltsch,Marianne G. Rots
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Epigenome Editing; Methods and Protocol Albert Jeltsch,Marianne G. Rots Book 2024Latest edition The Editor(s) (if applicable) and The Autho
描述.This second volume details new and updated methods covering applications of epigenome editing. Chapters guide readers through general and topical reviews, DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls... ..Authoritative and cutting-edge, .Epigenome Editing: Methods and Protocols, Second Editon .aims to ensure successful results in the further study of this vital field..
出版日期Book 2024Latest edition
关键词TALE; CRISPR; Zinc Fingers; Chromatin Immunoprecipitation; scFv–TET1 catalytic domain fusions
版次2
doihttps://doi.org/10.1007/978-1-0716-4051-7
isbn_softcover978-1-0716-4053-1
isbn_ebook978-1-0716-4051-7Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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书目名称Epigenome Editing读者反馈学科排名




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Plant Epigenetic Editing to Analyze the Function of Histone Modifications in Gene-Specific Regulatiot gene. We outline design principles and emphasize the need for suitable control constructs. In summary, the protocol will be widely useful for plant scientists looking to manipulate chromatin modifications in a locus-specific manner.
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Misurare e gestire il rischio finanziariodological considerations pertinent to neuroscience, such as delivery methods and the spatiotemporal specificity of editing and it demonstrates the enormous potential of epigenetic editing for basic neurobiological research and therapeutic application.
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Designing Epigenome Editors: Considerations of Biochemical and Locus Specificitiesiochemical diversity of chromatin; control for potential interdependency of epigenome editors and their resultant modifications; avoid sequestration effects; quantify the locus specificity of epigenome editors; and improve locus-specificity by considering concentration, affinity, avidity, and sequestration effects.
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