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Titlebook: Explorations in Aging; Vincent J. Cristofalo,Jay Roberts,Richard C. Adelm Book 1975 The Editor(s) (if applicable) and The Author(s), under

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https://doi.org/10.1007/978-3-319-89926-8y to respond biochemically to various stimuli (for reviews see Adelman, 1972; Roth and Adelman, 1974; Gusseck, 1972). Many responses of this type directly involve or are mediated by hormones (Roth and Adelman, 1974; Gusseck, 1972).
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Edward S. Kim,Bonnie S. Glissonnted and transferred to new organ culture dishes every 24 hr. The explants were bathed in Eagle’s minimal essential medium with Hanks’ salts and 10% calf serum, supplemented with glutamine and antibiotics.
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Harlan A. Pinto,Charlotte Jacobs of cells undergoing division within the cell population gradually declines (Phase III) and the culture is lost or transforms to a cell line which can be propagated indefinitely. This phenomenon has been described for cell cultures derived from human, mouse, chick, rat kangaroo, rabbit, and tortoise tissues.
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Hydrocortisone as a Modulator of Cell Division and Population Life Span,ase in the specific activity of these enzymes during cellular aging (1). Since these enzymes are typically marker enzymes for lysosomes, the findings implied that older cells contained more lysosomes, a conclusion that has since been documented by electron microscopic studies in our lab and by others (2–4).
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Function of Cardiac Muscle in Aging Rat,t. I would like to acknowledge the encouragement and critical comment of Dr. Nathan Shock and the efforts of Dr. Edward Lakatta and Dr. Gary Gerstenblith in designing and performing the more recent studies.
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