书目名称 | Exploration of Host Genetic Factors associated with Malaria |
编辑 | Tabish Qidwai |
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概述 | Summarizes host genetic polymorphisms that are associated with malaria susceptibility/resistance.Reviews molecular epidemiology and natural selection of alleles in genes associated with malaria.Examin |
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描述 | This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by .Plasmodium falciparum.. The chapters provide current information on the balancing trait and the significance of such traits in the malaria resistance. The book covers polymorphisms in the genes of the red blood cells-sickle cell anaemia; glucose-6-phosphate dehydrogenase deficiency and thalassemia that confer protection against malaria. In addition, the book explores selection of genetic variations in the human genome as genetic control mechanism against malaria in endemic regions. It also provides a comprehensive overview of the molecular epidemiology and natural selection of alleles in the genes which are associated with malaria, and presents description of the role of human genetic polymorphisms in malaria disease risk and disease outcome.. |
出版日期 | Book 2021 |
关键词 | Malaria; Host genetic factor; Balanced polymorphisms; Resistance allele; Immune response; infectious dise |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-33-4761-8 |
isbn_softcover | 978-981-33-4763-2 |
isbn_ebook | 978-981-33-4761-8 |
copyright | Springer Nature Singapore Pte Ltd. 2021 |