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Titlebook: Exploration of Host Genetic Factors associated with Malaria; Tabish Qidwai Book 2021 Springer Nature Singapore Pte Ltd. 2021 Malaria.Host

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书目名称Exploration of Host Genetic Factors associated with Malaria
编辑Tabish Qidwai
视频video
概述Summarizes host genetic polymorphisms that are associated with malaria susceptibility/resistance.Reviews molecular epidemiology and natural selection of alleles in genes associated with malaria.Examin
图书封面Titlebook: Exploration of Host Genetic Factors associated with Malaria;  Tabish Qidwai Book 2021 Springer Nature Singapore Pte Ltd. 2021 Malaria.Host
描述This book is aimed to cover the role of genetic polymorphisms in human genes related to RBC disorders, metabolic enzymes, immune response, and cytoadherence in the susceptibility/resistance to malaria caused by .Plasmodium falciparum.. The chapters provide current information on the balancing trait and the significance of such traits in the malaria resistance. The book covers polymorphisms in the genes of the red blood cells-sickle cell anaemia; glucose-6-phosphate dehydrogenase deficiency and thalassemia that confer protection against malaria. In addition, the book explores selection of genetic variations in the human genome as genetic control mechanism against malaria in endemic regions. It also provides a comprehensive overview of the molecular epidemiology and natural selection of alleles in the genes which are associated with malaria, and presents description of the role of human genetic polymorphisms in malaria disease risk and disease outcome..
出版日期Book 2021
关键词Malaria; Host genetic factor; Balanced polymorphisms; Resistance allele; Immune response; infectious dise
版次1
doihttps://doi.org/10.1007/978-981-33-4761-8
isbn_softcover978-981-33-4763-2
isbn_ebook978-981-33-4761-8
copyrightSpringer Nature Singapore Pte Ltd. 2021
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,Sociology as “Just an Academic Pursuit”,of disease. This chapter is aimed to investigate the possible association of malaria with alpha-thalassaemia among different populations of the world. It would be helpful in identification of new therapeutic approach in malaria prevention and control.
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https://doi.org/10.1007/978-3-658-36746-6A sequence variations in human genome. Many genetic variations in G6PD have been reported in various ethnic populations and accountable for deficiency/decreased activity of enzyme. Therefore, study of the host genetic control mechanisms such as G6PD deficiency and its role in malaria resistance in d
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Hast Du auch hohes Cholesterin?e resistance against malaria in endemic regions. Exploration of polymorphisms in . gene will be important in identification of genetic risk of a population to malaria. Moreover, enzyme and its product (iNOS/NO) probably act as possible diagnostic marker in evaluating clinical malaria.
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https://doi.org/10.1007/978-3-662-28626-5tion. Investigation of genetic variations in . gene and its role in susceptibility/resistance to malaria in different population will be important to understand the risk of population to malaria, particularly in endemic regions. The aim of present chapter is to analyze the . polymorphisms and their
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https://doi.org/10.1007/978-1-4899-6108-2 variations of . may affect the severity and outcome of . malaria in different populations. The high incidence of malaria in endemic regions forces the human genomes to select the genetic variations of human genes involved in pathogenesis of malaria. This chapter is aimed to investigate the . polymo
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Aktivismus- und Propagandaforschung, regulatory polymorphisms affect expression of gene (level of gene product) while coding polymorphisms affect protein structure and hence activity. Polymorphisms in . gene have been shown to influence the cytoadherence process and therefore alter the disease severity. In malaria endemic regions, hi
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Alpha-Thalassemiaof disease. This chapter is aimed to investigate the possible association of malaria with alpha-thalassaemia among different populations of the world. It would be helpful in identification of new therapeutic approach in malaria prevention and control.
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