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Titlebook: Experimental Neurotoxicology Methods; Jordi Llorens,Marta Barenys Book 2021 Springer Science+Business Media, LLC, part of Springer Nature

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楼主: Deleterious
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DPOAEs for the Assessment of Noise- or Toxicant-Induced Cochlear Damage in the Ratrovide a detailed method to measure DPOAEs in rats. We emphasize especially on the calibration of the sound stimulation and the analysis of the otoacoustic emissions, which ensure the reliability of the method.
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Assessment of Auditory Hair Cell Loss by Cytocochleograms considered species provides a wealth of information, both quantitative and objective, on the type and severity of the exposure. This article describes a method to (1) harvest the cochlea, (2) stain and dissect the organ of Corti, (2) quantify the hair cell loss, and (3) construct a graphic represen
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Use of Visual Evoked Potentials to Assess Deficits in Contrast Sensitivity in Rats Following Neurotoual patterns. The resulting evoked potentials are signal averaged, subjected to spectral analysis and interpreted relative to the contrast of the eliciting visual patterns. The resulting parameters include measurements of response amplitude, contrast threshold, contrast sensitivity, and contrast gai
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Assessment of Olfactory Toxicity in Rodentssts evaluating olfactory discrimination or olfactory thresholds in exposed animals. These more complicated tests often require specialized equipment and extensive training of the animal to display an odor-mediated behavior. This chapter provides an update of our current understanding of chemically i
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Assessment of Neurotoxicant-Induced Changes in Behavior : Issues Related to Interpretation of Outcomnge in behavior, particularly for cognitive/executive functions, such as learning. Additionally, this chapter addresses issues related to the use and misuse of test batteries and the influence of the behavioral history resulting from use of a test battery that may interact with the toxicant treatmen
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