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Titlebook: Experimental Hematology Today—1985; Selected Papers from S. J. Baum,Dov H. Pluznik,L. A. Rozenszajn Conference proceedings 1986 Springer Sc

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Risk Factors for Acute Graft-vs-Host Disease in Humansbelieved to be targets of acute GVHD. Despite considerable data in animal models and in humans, the precise role of other effector mechanisms such as humoral immunity, antibody-dependent cellular cytotoxicity, natural killer cells, lymphokines, and the monocyte-macrophage system, remain controversial.
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Autologous Marrow Transplantation for Malignant Lymphomaial Seattle experience with autologous marrow transplantation as treatment for patients with relapsed or resistant malignant lymphoma and compares this approach with our previously published experience using syngeneic and allogeneic transplantation in a similar group of patients (3–5).
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Role of T-Lymphocyte Colony Enhancing Factor, TLCEF, in the Induction of CFU-TLtinin (PHA). Using a preparation of partially purified TLCEF, which was devoid of other interleukin activities, it was possible to demonstrate that TLCEF was responsible for the enhancement of Type I colony formation in two-step cultures. On the other hand, interleukin-2 (IL-2), and not TLCEF, was s
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Early Biochemical Steps in Colony Stimulating Factor (CSF) Generation are Induced by Synergy betweenhate (InsP3). DAG activates protein kinase C (PK-C) and InsP3 mobilizes intracellular calcium. Both tumor promoting phorbol esters (TPA) which activate PK-C directly and calcium ionophores which mobilize intracellular calcium bypass inositol phospholipid breakdown. We recently reported that the inte
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Dependence of CFU-S Proliferation on the CFU-S Populationifferent regions of haemopoietic tissue. In the leg shielding experiments, cellularity, spleen colony-forming unit (CFU-S) content and proliferative activity return to normal in the shielded limb long before they do in the rest of the animal. (5). Following phenylhydrazine (PHZ), demand for erythroi
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In Vivo Effects of Urinary Extracts of Patients with Aplastic Anemia on Rat Platelet Production and s after administration of urinary extracts from patients with aplastic anemia (AA). Single intraperitoneal injections of 140 μg and 30 μg of protein (65–90% ethanol precipitate of crude urinary preparation) were administered to Sprague-Dawley rats and BDF. mice, respectively. Circulating platelet co
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