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Titlebook: Excitotoxins; Proceedings of an In Kjell Fuxe,Peter Roberts,Robert Schwarcz Conference proceedings 1983 Springer Science+Business Media New

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Electrophysiological Actions of Kainate and Other Excitatory Amino Acids, and the Structure of Theirace. It should however be noted that more recent evidence has been obtained indicating that the reaction of more than one molecule of an amino acid is required for functional activation to occur (McLennan and Wheal, 1976a). It was further noted that the “receptor” was not stereoselective, although f
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Two Types of Excitatory Amino Acid Responses in the Cat Caudate Nucleused the same effects. Aspartic acid showed mixed effects but type 1 always seemed to predominate..At low doses, the antagonist D-alpha-aminoadipic acid inhibited only type 2 effects, whereas higher doses also reduced type 1 responses. On the same cells, however, antagonism of type 2 effects was alway
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Excitotoxins: An Overviewnus for which we must indeed be grateful. But there are many gaps in our understanding of these agents, gaps which can only be filled by years of methodical research, but gaps which must be filled if we are to decipher the roles of ET in the physiology and pathology of the CNS and realize their full
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The Neurodegenerative Properties of Intracerebral Quinolinic Acid and its Structural Analog Cis-2,3-e merely yielded equivocal results (Perry et al., 1975; Gray et al., 1980; Perry and Hansen, 1981; Mangano and Schwarcz, 1981, 1982). Their dysfunction in neuro-psychiatric disorders has as yet not been established.
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Studies on Excitatory Amino Acid Receptors and Their Interactions and Regulation of Pre- and Postsynd, at least in the striatum where the present experiments indicate that activation of glutamate receptors increases the number of .H-kainic acid binding sites, so that they may reach a certain critical number required for neurotoxicity. Furthermore, kainic acid by increasing the affinity of the .H-g
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Springer Series in Optical Sciencesace. It should however be noted that more recent evidence has been obtained indicating that the reaction of more than one molecule of an amino acid is required for functional activation to occur (McLennan and Wheal, 1976a). It was further noted that the “receptor” was not stereoselective, although f
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