Titlebook: Evolving Methods for Macromolecular Crystallography; The Structural Path Randy J. Read,Joel L. Sussman Conference proceedings 2007 Springe

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书目名称Evolving Methods for Macromolecular Crystallography被引频次学科排名




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书目名称Evolving Methods for Macromolecular Crystallography年度引用学科排名




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书目名称Evolving Methods for Macromolecular Crystallography读者反馈学科排名

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Macromolecular cryo-crystallography,ly collected with the sample held at around 100 K, significantly reducing the secondary radiation damage, and usually resulting in higher resolution and better quality data. However, at synchrotron X-ray sources, even at cryo-temperatures there has now been frequent observation of both degradation o

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Processing diffraction data with mosflm,crystal; second, obtaining refined values for these parameters; and third, integrating the diffraction images. The basic principles underlying autoindexing, parameter refinement, and spot integration by summation integration and profile fitting are described.

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Stochastic molecular replacement,mensionality. Due to their divide-and-conquer approach, these methods necessarily ignore (at least during their early stages) the very knowledge that a target crystal structure may comprise, for example, more than one copy of a search model, or, several models of different types. Here, we describe a

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Structural genomics of mycobacterium tuberculosis: a search for function and new drug targets,o the discovery of function from structure, and the characterization of new drug targets. The TB Structural Genomics Consortium (TBSGC), an international collaboration of more than 50 laboratories, was formed to address the worldwide problem of TB, through its focus on ., the causative agent. The go