Titlebook: Evolutionary Systems Biology; Advances, Questions, Anton Crombach Book 2021Latest edition The Editor(s) (if applicable) and The Author(s),

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Anton CrombachIllustrates the blossoming synergy of theory and experiment in biology.Highlights the value of evolutionary systems biology for a better understanding in (systems) genetics, synthetic biology, and met

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978-3-030-71739-1The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl

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https://doi.org/10.1007/978-3-030-71737-7evolution; development; theory; experiment; systems biology

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Determination of Nuclear Quadrupole Moments,ut this question is surprisingly overlooked by evolutionary systems biology. This comes unexpected given the roots of systems biology in complex systems science but also given that a proper understanding of the origin and evolution of complexity would provide clues for a better understanding of exta

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https://doi.org/10.1007/978-3-030-39578-0replication, as well as the robustness of phenotypes against perturbations. Adaptive changes in high-dimensional phenotypes were shown to be restricted within a low-dimensional slow manifold, from which a macroscopic law for cellular states was derived, which was confirmed by adaptation experiments

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Experimental Investigations of the EHVE,volution. The aim is a mechanistic understanding of the genotype-phenotype map and its evolution. Our review focuses on the case study of the gap gene network in dipteran insects (flies and midges). This network is the top regulatory tier of the segmentation gene hierarchy, generating a pattern of o

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,Das Marketingverständnis der Arbeit, phenotypes stems from the complexity of multi-cellular systems, where thousands of genes and cells interact with each other providing developmental non-linearity. To understand how diverse morphologies have evolved, it is essential to find ways to handle such complex systems. Here, we review the fi