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Titlebook: Evolutionary Systems Biology; Orkun S. Soyer Book 20121st edition The Editor(s) (if applicable) and The Author(s), under exclusive license

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https://doi.org/10.1007/978-981-15-4786-7very different biological functions: multistability, adaptive networks and entire developmental programmes like somitogenesis and . gene pattern. In silico evolution finds both known and original network designs, and can be used to make predictions on biological behaviours. This computation illustra
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Karel Jansen,E. V. K. FitzGeraldotype distribution. Plasticity concerns the response of a phenotype against environmental and genetic changes, whereas robustness is the degree of insensitivity against such changes. Note that the sensitivity increases with the variance, and the inverse of the variance works as a measure of the robu
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International Finance and Development Seriestory networks. We summarize results from three complementary approaches that explicitly represent biological processes of transcription, translation, metabolism and gene regulation: a fine-grained model that allows detailed molecular interactions, a coarse-grained model that allows rapid evolution o
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Ketevan Bolkvadze,Bidzina Lebanidzeolution of bacterial resistance and phage infectivity (antagonistic coevolution). Such coevolution can have profound consequences at all levels of biological organisation. Here, we review genetic and ecological factors that contribute to determining coevolutionary dynamics between bacteria and phage
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