Titlebook: Etiology: Chemical and Physical Carcinogenesis; Frederick F. Becker Book 1982 Springer Science+Business Media New York 1982

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Development Education in Policy and Practiceollowing: “the understanding of natural immunity really represents the key to carcinoma.... I have acquired the firm conviction that natural immunity does not depend on the presence of anti-microbial materials, but rather, it depends on purely cellular activities. I am certain that, in the enormousl

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https://doi.org/10.1007/978-3-319-54166-2se elements are limited by our science and indeed by our vocabulary. In the ideal model one agent acting on one host would cause one disease. In an attempt to approximate this model, we instead say this host will more often develop this disease if exposed to this agent than if not exposed. The agent

intuition

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Anthony Clunies-Ross,John Langmoree 18th century that human scrotal cancer in Great Britain was associated with the occupation of his affected patients as chimney sweeps. Since that time, people in other occupations have been demonstrated to have certain risks of developing cancer at some sites. Overall, however, occupational cancer

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https://doi.org/10.1057/9781137463661ation of procarcinogens to reactive ultimate carcinogens, (2) the characterization of interactions of the active metabolites of many carcinogens with a variety of tissue nucleophiles including DNA, RNA, and protein, and (3)the development of model systems for a sequential analysis of the initiation

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Fabiana Sciarelli,Azzurra Rinaldiver cells were reviewed briefly. That review covered the period from the emergence of the application of ultrastructural studies to the problem of carcinogenesis in the early 1960s through publications available in 1972. The purpose of this chapter is to present several observations regarding effect

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Manuel Mora,Fen Wang,Hector Duran-Limonse skin combined with, or following, tar painting (Deelman, 1924; Deelman and van Erp, 1926), and later, from combined applications of carcinogenic hydrocarbons with (noncarcinogenic) creosote oil (Sall .., 1940). But the establishment of sequential stages in carcinogenesis arose by the convergence

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John B. Kidd,Frank-Jürgen Richter populations appear sequentially as possible precursor lesions for the next step (Foulds, 1969, 1975; Farber, 1973.; Farber and Cameron, 1980; Farber and Sporn, 1976; Medline and Farber, 1980). The multistep patterns appear to occur in most known instances of cancer induced by chemicals and radiatio

OREX

Hilary Footitt,Angela M. Crack,Wine Tesseurmal cell counterpart, at least in the adult host. In early studies with chemically induced tumors (Foley, 1953; Baldwin, 1955; Prehn and Main, 1957), neoantigens were defined by their capacity to elicit immunity to transplanted tumor and were termed “tumor-specific transplantation antigens.” It is n

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