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Titlebook: Estrogens and Brain Function; Neural Analysis of a Donald W. Pfaff Book 1980 Springer-Verlag New York Inc. 1980 Brain.Function.Gehirn.Hormo

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Ascending Neural Pathwaysemale rats were studied before and after complete transection of the spinal cord at low thoracic levels. All sham-operated rats showed strong lordosis reflexes before and after surgery. None of the rats receiving complete spinal transections performed lordosis after surgery, even in tests done 3 mon
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Hypothalamic Mechanismsy estrogen in female rats, estrogenic influences on hypothalamic cells are considered primary. In fact, in a wide variety of vertebrate species, estrogens restore sexual receptivity to castrated females (Kelley and Pfaff, 1978). The accumulation of radioactive estradiol by hypothalamic nerve cells i
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Hypothalamic Outflowwith hypothalamic cell groups can disrupt food intake, drinking, temperature regulation, aggressive behavior, emotional responses, maternal functions, sleep, arousal, secretion of hormones from the pituitary, and reproductive behavior. Regarding lordosis, hypothalamic axons descending to the midbrai
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Brainstem to Spinal Cord brainstem is obligatory, and its net effect must be to facilitate the behavior. Such descending fibers must run in the anterolateral columns (broadly defined), since these are necessary and sufficient for lordosis (Kow et al., 1977). The critical fibers must reach lumbar levels, since the crucial h
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Motoneurons and Response Executionneurons. We proceed to discover how this occurs by working our way in from the form of the behavioral response itself to the spinal neural mechanisms that determine that form. Precise descriptions of the behavioral response provide the platform from which studies of the responsible muscles can be la
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Logical and Heuristic Developmentspeak to issues longstanding in the neural control of behavior; in other cases new concepts may be induced. Some principles of operation arise from the input (ascending) side of the lordosis behavior circuit (Sections B and C); other features have more to do with the middle of the circuit (Sections D
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