Titlebook: Essentials of Clinical Research; Stephen P. Glasser Textbook 2014Latest edition Springer International Publishing Switzerland 2014 clinica

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Research Methods for Genetic Studies,genetic epidemiology studies to clinicians. An overview of genetic association studies is provided, which is the current state-of-the-art for clinical and translational genetics. Discussion of future directions in this field is also included.

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Association, Cause, and Correlation,may not be. This chapter will address the various ways one can measure the degree of association between an exposure and an outcome and will include a discussion of relative and absolute risk, odds ratios, number needed to treat, and related measures. In addition, this chapter will introduce the concept of causal inference.

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,It’s All About Uncertainty,! We will start with the concepts of “the universe” and a “sample”, discuss the conceptual issues of estimation and hypothesis testing and put into context the question of how certain are we that a research result in the sample studied reflects what is true in the universe.

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Stephen P. GlasserThoroughly updated and expanded for the Second Edition.Includes new material on the net reclassification index; the p value and Bayesian approaches and more.Offers new discussion of clinical practice

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https://doi.org/10.1007/978-3-8349-9464-6This chapter addresses some of the central concepts related to clinical research such as sampling, hypothesis generation, and what is meant by the strength of scientific evidence. We also begin to discuss the different clinical research designs along with their respective strengths and weaknesses.

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Introduction to Clinical Research Concepts, Essential Characteristics of Clinical Research, OvervieThis chapter addresses some of the central concepts related to clinical research such as sampling, hypothesis generation, and what is meant by the strength of scientific evidence. We also begin to discuss the different clinical research designs along with their respective strengths and weaknesses.