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Titlebook: Essential Oncology of the Lymphocyte; Ian J. Forbes,Anthony S-Y. Leong Book 1987 Springer-Verlag Berlin Heidelberg 1987 cancer.diseases.ly

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Derangement of the Genome as a Cause of Cancer,s an abnormality of the genome. Several kinds of abnormality may be involved: abnormal regulation, i.e. over- or underactivation of genes, failure of expression of genes, or alteration of a gene resulting in a product that vitally affects cell function.
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The Lymphoid Tissues,ells of the monocyte-macrophage series, which are collectively called accessory cells (ACs) are essential for generation of both cellular and humoral (antibody) responses. They play a large part in regulating immune responses, by presenting antigen to T and B cells, by degrading antigen and by release of mediators.
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Multiple Steps in the Genesis of a Cancer,essive stages of carcinogenesis can be enhanced or inhibited in some experimental situations by different types of agent (Weinstein et al. 1984), indicating that individual phases may involve different mechanisms.
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The Major Histocompatibility Complex,e target cells express the same MHC class I product on their surface membranes. Whether immunological surveillance is effective against potentially malignant mutants is still not clear. The MHC is essential for recognition of one cell of the immune system by another, for recognition of genetically f
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