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Titlebook: Erythropoietin and the Nervous System; Ahmet Höke (Associate Professor of Neurology and N Book 2006 Springer-Verlag US 2006 Nervous System

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https://doi.org/10.1007/978-3-642-40044-5f rhEPO are not limited to direct effects on neurons. System administration of rhEPO in animals given a chronic constriction injury to the sciatic nerve, a model known to produce the pro-inflammatory cytokine, TNF-α, at the injury site results in significant reductions in Schwann cell produced TNF-α
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International Management Knowledgedicating that one of the mechanisms by which inflammation promotes and extend damage could be through inhibition of EPO production. Thus, EPO should be viewed as part of the inflammation/anti-inflammation network in the CNS.
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