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Titlebook: Erythropoietin and the Nervous System; Ahmet Höke (Associate Professor of Neurology and N Book 2006 Springer-Verlag US 2006 Nervous System

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发表于 2025-3-21 16:39:47 | 显示全部楼层 |阅读模式
书目名称Erythropoietin and the Nervous System
编辑Ahmet Höke (Associate Professor of Neurology and N
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概述The first book of its kind that brings together researchers from many different disciplines of neuroscience together to review the current state-of-the-art in EPO and the nervous system.Includes suppl
图书封面Titlebook: Erythropoietin and the Nervous System;  Ahmet Höke (Associate Professor of Neurology and N Book 2006 Springer-Verlag US 2006 Nervous System
描述.Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition to its traditional role as a hormone that stimulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with relatively safety profile of this FDA-approved drug makes it an ideal candidate to take it into clinical trials for neuroprotection. We are on the verge of major clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse myelitis to chemotherapy-induced peripheral neuropathy. This is the first book of its kind that brings together researchers from many different disciplines of neuroscience to review the current state-of-the-art in EPO and the nervous system. This book will benefit scientists and clinicians interested in neuroprotection in the broadest sense..
出版日期Book 2006
关键词Nervous System; brain; central nervous system; death; hypoxia; inflammation; neuroprotection; neuroscience;
版次1
doihttps://doi.org/10.1007/978-0-387-30011-5
isbn_softcover978-1-4899-7383-2
isbn_ebook978-0-387-30011-5
copyrightSpringer-Verlag US 2006
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发表于 2025-3-21 22:27:58 | 显示全部楼层
,A Review of China’s Economy in 2013, way to the bone marrow where it regulates red cell production by preventing apoptosis of erythroid progenitor cells. Recently, EPO has emerged as a multifunctional growth factor that plays a significant role in the nervous system. Both EPO and its receptor are expressed throughout the brain in glia
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Current Chinese Economic Report Seriesen identified by the meticulous work of many excellent research groups. The aim of this chapter is to identify and discuss the key signaling molecules and events published in numerous reports that are involved in EPO mediated neuroprotection. In order to provide a better overview, the signaling mole
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https://doi.org/10.1007/978-981-19-8536-2) is a physiological response to hypoxia in oxygen-deprived tissues. Hypoxia-induced epo gene expression is regulated by the transcriptional activator hypoxia inducible factor (HIF). The epo gene contains a HIF binding site in its 3′ untranslated region, and its expression is upregulated concomitant
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Current Chinese Economic Report Seriesin maturation and contribute to variable patterns of brain injury in preterm and term neonates after HI. Following HI, a multifactorial cascade is initiated that injures the developing brain and can lead to significant morbidity and mortality. Despite intense investigation, no effective intervention
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,Forecast of China’s Economy for 2014–2015,ursors in the bone marrow. EPO and EPO receptor protein are also expressed by CNS neurons and glial cells. EPO exerts neuroprotective effects in various experimental in vitro and in vivo models of neural injury, such as mechanical trauma, neuroinflammation, and cerebral and retinal ischemia. In this
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